About eLife

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Senior editors

  1. Philip Cole

    Senior Editor

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    Expertise
    Cell Biology
    Competing interests statement
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  2. Ivan Dikic

    Senior Editor

    Ivan Dikic is a Professor and Chairman of Institute of Biochemistry II at the Medical School Goethe University and a member of the Buchmann Institute for Molecular Life Sciences in Frankfurt. He was trained as a medical doctor at Zagreb University and obtained his PhD in molecular biology with Joseph Schlessinger. His career is focused on studying intracellular signaling initially via protein tyrosine kinases where he revealed how multiple monoubiquitination controls EGFR endocytosis. His lab has pioneered a concept of Ubiquitin as a multivalent cellular signal that regulates multitude of physiological and pathophysiological processes including DNA repair, inflammation, cancer, infection and proteasomal degradation. Ivan’s group also provided structural and functional evidence for a new type of Ub chains that are Met1-linked (called linear ubiquitination) in promoting the NF-kB signaling. His current interests focus on selective autophagy, which is essential for the clearance of protein aggregates, pathogens, and damaged mitochondria from the cell. He has received many awards for his work including the AACR Award for Outstanding Achievement in Cancer Research, the Award of European Association for Cancer Research, the Hans Krebs Prize, the Leibniz Award and the Ernst Jung Award in Medicine. He is a Member of the German Academy for Sciences Leopoldina, Academia Europaea, Croatian Academy of Medical Sciences and the European Molecular Biology Organization.

    Expertise
    Biochemistry
    Cell Biology
    Research focus
    ubiquitination
    autophagy
    endocytosis
    inflammation
    cancer biology
  3. John Kuriyan

    Senior Editor

    John Kuriyan is Professor of Molecular and Cell Biology and also of Chemistry at the University of California, Berkeley. Before this, he was on the faculty at The Rockefeller University, New York, where he began his career in 1987, leaving for Berkeley in 2001. Since 1990, he has been an Investigator of the Howard Hughes Medical Institute. Kuriyan completed undergraduate studies in chemistry at Juniata College, Huntingdon, PA. His doctoral research, on the dynamics of proteins, was carried out at MIT, under the guidance of Greg Petsko and Martin Karplus (Harvard University). Kuriyan’s research is aimed at understanding the structure and mechanism of the enzymes and molecular switches that carry out cellular signal transduction and DNA replication. His laboratory uses x-ray crystallography to determine the three-dimensional structures of proteins involved in signaling and replication, as well as biochemical, biophysical, and computational analyses to elucidate mechanisms. Kuriyan was elected to the US National Academy of Sciences in 2001.

  4. Wenhui Li

    Senior Editor

    Wenhui Li is an Investigator of the National Institute of Biological Sciences (NIBS), Beijing, China. He received a bachelor’s degree in medicine from the Medical School of Lanzhou University in 1994 and his PhD from the Peking Union Medical College & Chinese Academy of Medical Sciences in 2001. After completing his postdoctoral studies at Harvard Medical School, Li joined NIBS as an Assistant Investigator in 2007 and rose to the rank of Investigator in 2015. His team at NIBS identified a liver bile acids transporter (sodium taurocholate co-transporting polypeptide, NTCP) as a functional receptor for Hepatitis B and D virus. Li’s research interest has been focusing on the molecular mechanisms of viral infections: currently his laboratory combines virology, biochemistry, immunology, and chemical biology to investigate molecular mechanisms of HBV/HDV infection.

  5. Vivek Malhotra

    Senior Editor

    Vivek Malhotra was a professor in the biology division at UC San Diego from 2007 and is now the ICREA Professor and Chair of the Cell and Developmental Biology at Center for Genomic Regulation (CRG) in Barcelona. His research focuses on a central station of the secretory pathway, the Golgi complex. Specifically, his work has resulted in the identification of the machinery required for the sorting and packaging of secretory cargoes. His recent work has uncovered a novel secretory routing that bypasses the conventional pathway of protein secretion. He has identified new genes required for the export of bulky collagens and the regulated secretion of mucins. He received his BSc from Stirling University and was a Pirie–Reid scholar at Oxford; a Damon Runyon Walter Winchell and an American Cancer Society postdoctoral fellow at Stanford; and Basil O’Conner scholar, established Investigator of the American Heart Association, and Senior Investigator of Sandler’s Foundation for Asthma at UC San Diego. He received the MERCK award from the American Society of Biochemistry and Molecular Biology, is a fellow of the American association of the arts and science, and is an elected EMBO member.

  6. Laurent Gatto

    University of Cambridge, United Kingdom

    I am a Senior Research Associate in the Department of Biochemistry at the University of Cambridge, where I lead the Computational Proteomics Unit. I am an avid open research advocate and make very possible effort to make my research reproducible. I am a Software Sustainability Institute fellow and a Data/Software Carpentry instructor and a member of OpenConCam, our local OpenCon group. My current open researcher activities focus on the Wellcome Trust Open Research Project, where we explore the barriers to open research, and the Bullied Into Bad Science campaign, an initiative by and for early career researchers who aim for a fairer, more open and ethical research and publication environment.

    For more information see Laurent's personal website https://lgatto.github.io/

    Expertise
    Computational and Systems Biology
    Research focus
    computational biology
    proteomics
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